One-pot three-component tandem annulation of 4-hydroxycoumarine with aldehyde and aromatic amines using graphene oxide as an efficient catalyst

Abstract A convenient and efficient solvent-free, facile, one-pot three-component graphene oxide catalysed approach has been described for the synthesis of chromeno-[4,3-b]quinolin-6-one derivatives Medical Cart from 4-hydroxycoumarin with aldehydes and aromatic amines.Graphene oxide (GO) has proved to be a new class of heterogeneous carbocatalyst which could be easily recovered and reused up to 5th Sandals run without significant loss of its catalytic activity.A broad scope of substrate applicability is offered and a plausible mechanism is also suggested for this developed protocol.